About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

At AbbVie, we are dedicated to solving some of the worlds most complex and serious diseases. Our mission is to develop and deliver advanced therapeutics that change lives. The Discovery Neuroscience In Vivo Pharmacology group in Cambridge, Massachusetts, is seeking a highly skilled and self-motivated Senior Scientist to join a dynamic team supporting target identification, validation, and drug transport facilitation over brain barriers. The successful candidate will drive scientific innovation, has experience making tangible contributions to the discovery pipeline, and has people and project management experience.

Responsibilities:

• Responsible for design and implementation of in vivo testing of multispecific biologics, small molecules, and siRNAs to support projects in the areas of Alzheimers and Parkinsons disease
• Serve as an in vivo representative in cross-functional teams with Discovery Biotherapeutics, DMPK, and Development Sciences colleagues, providing project updates, analysis, and strategic advice
• Proactively translatedepartment/projectteam scientific questions into well-designed experiments,utilizinginternal and external resources
• Identify and solve technical problems independently, implement new assays and workflows, conceive and implement innovative research ideas
• Analyze and interpret multidisciplinary data to generate actionable conclusions and guide future experimental directions
• Collaborate with cross-functional partners at various AbbVie sites to advance candidates through discovery milestones
• Work independently and maintain a high level of productivity in the laboratory, ensuring efficiency and scientific rigor
• Mentor / matrix managejunior scientists, and be accountable for the effective performance of the team
• Ensure consistency and quality of technical reports
• Upholdimpeccableresearch-related&corporate compliancestandards
• May author or co-author peer-reviewed scientific papers or patents

Minimum Qualifications:

• Bachelors Degreeand typically, 12 years of experience, Masters Degreeand typically 10 years of experience, PhD and typically 4 years of experience.
• Background in receptor and / or transporter biology and targeted delivery
• Background in brain barriers biology
• Experience with in vivo models of neurodegeneration, particularly with models of Alzheimers and Parkinsons Disease
• Experience in assay development for target identification and validation, mechanism of action studies, biodistribution and biomarker analysis. Proven ability to troubleshoot and refine assays and workflows
• Proven track record in characterizing complex biotherapeutics in vivo (biologics, small molecules, siRNA)
• Proven track record of working in multidisciplinary in vivo pharmacology teams, demonstrated ability to collaborate effectively in a dynamic, cross-functional matrix environment
• Experience managing direct reports, including providing performance evaluations and development opportunities
• Excellent organizational skills, strong data analysis and critical thinking skills, and the ability to manage multiple projects simultaneously
• Goal-oriented and highly self-motivated team player with excellent verbal and written communication skills with experience contributing to technical reports and publications

Desired Qualifications:

• Experience operating effectively in a matrixed, fast-paced discovery organization
• Experience in managing external collaborations
• Experience with ex vivo readouts including immunohistochemistry and biochemistry (e.g., ELISA, WB, qPCR, ddPCR). Experience with image analysis
• Familiarity with CNS-relevant biology and genetic medicine applications

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

• This job is eligible toparticipatein our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

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https://www.abbvie.com/join-us/reasonable-accommodations.html